This essay is a defense of rationally normative ethics and individualism. Communitarians remedy the shortcomings of deontology's conception of the self as disembodied, asocial, and willful by reuniting reason and desire and by regarding reason as a principle of coordination within a social or communal context. While this renders reason more efficacious than it can be on the deontological view, it still falls short of the aspiration of Western ethics for rational control over theformation of moral judgments; reason and the (...) individual in whom it resides are subordinated to the social. In order for there to be a truly rational norm of moral decision-making, reason must have a constitutive function. That is, reason must not only seek coordination or harmony among elements other than and beneath itself, but it must also be capable of realizing and perpetuating itself in that harmony. A certain kind of harmony is thus sought, one in which reason (self-aware, self-possessed, and self-determined agency) rules the soul. This ethical position is frankly realistic from a metaphysical point of view and is opposed to nominalistic theories of personhood. It is argued that nominalistic accounts of personhood which would exclude the unborn and others from the class of persons or rational agents are logically inconsistent. (shrink)

In 1839 and 1840, Newman preached four Oxford University Sermons, which critiqued the evidential apologetics advocated by John Locke (1632-1704) and William Paley (1743-1805) and subsequently restated by Richard Whately (1787-1863). In response, Newman drew upon Whately’s earlier works on logic and rhetoric to develop an alternative account of the reasonableness of religious belief that was based on implicit reasoning from antecedent probabilities. Newman’s argument was a creative response to Whately’s contention that evidential reasoning is the only safeguard against (...) superstition and infidelity. (shrink)

John Henry Newman wrote the “Theses de Fide” in Rome as a seminary student in 1846/1847, and the text represents a key point in the development of his thought. Newman wrote the “Theses” in an attempt to grapple with scholastic categories on faith, a question that had occupied him in the Anglican Church for years. Although the “Theses” were not published in Newman’s life, he returned to these reflections often over the course of his Roman Catholic career. This edition (...) and partial translation of the “Theses de Fide” is to aid general readers in understanding this moment in Newman’s life, and to assist specialists in approaching the manuscript record of the “Theses” themselves. (shrink)

John King-Farlow's ‘The Positive McTaggart on Time’ brings out extremely important likenesses between ‘abstract’ metaphysicians and ‘concrete’ philosophers of science. These striking similarities illustrate a perennial human quest for Something More Basic than Time, a quest which characterizes not only mystics who rejoice in contradictions but hard-headed philosophers who submit to the rigours of logic. King-Farlow is largely concerned with the McTaggart of 1908 and his motivation for writing ‘The Unreality of Time’. I should like to explore further the (...) surprising bond between the Search for Something Deeper in the later McTaggart of The Nature of Existence and the writings on Time of Hans Reichenbach and Adolf Grünbaum. Reflection on this similarity should enable us better to evaluate the view that our vulgar, if practically useful, assertions about Time's Arrow must be reinterpreted by the wise in terms of chastened logical constructions out of statements about Something Deeper—logical constructions which are alleged, if chaste enough, to be eliminable. (shrink)

John McDowell’s recent collection of essays, _Having the World in View: Essays on Kant, Hegel, and Sellars_ is a penetrating work that builds upon insights from Kant, Hegel, and Sellars in order to articulate “an idealism that does not diverge from common-sense realism,” a view according to which “thought and the world must be understood together” (p. 143). McDowell argues that the insights from Kant, Hegel, and Sellars should enable us to see that certain perennial philosophical difficulties concerning how (...) thought is related to empirical reality are in fact based on mistaken, noncom- pulsory views about the nature of intentionality in general, and about the relationship between free human rationality and passive sensory intake from the world in particular. In this critical notice I first highlight some central issues that reappear throughout the essays, and then I raise some questions concerning issues both internal to McDowell’s account and in relation to the ways in which his views clash with those of Sellars in particular. (shrink)

The initial impact of John Henry Newman’s 1845 Essay on the Development of Christian Doctrine has previously been downplayed because scholars have neglected Roman sources on the question. These sources show that one of the most influential theologians in Rome at the time, Giovanni Perrone, S.J., learned from Newman’s theory and even advocated it publically in the city. After an 1847 exchange with Newman on the question of doctrinal development, Perrone employed Newman’s theory in publications that contributed to the (...) discussions preceding the decree of the Immaculate Conception in 1854. The article goes on to illustrate how Perrone’s influence upon these discussions helped to shape the Church’s official language regarding doctrinal progression in history. (shrink)

This collection of new essays on the systematic thought and intellectual legacy of the American philosopher Wilfrid Sellars (1912–1989) comes at a time when Sellars’s influence on contemporary debates about mind, meaning, knowledge, and metaphysics has never been greater. Sellars was among the most important philosophers of the twentieth century, and many of his central ideas have become philosophical stock-in-trade: for example, his conceptions of the ‘myth of the given’, the ‘logical space of reasons’, and the ‘clash’ between the ‘manifest (...) and scientific images of man-in-the-world’. This volume of well-known contemporary philosophers who have been strongly influenced by Sellars – Robert Brandom, Willem deVries, Robert Kraut, Rebecca Kukla, Mark Lance, John McDowell, Ruth Millikan, James O’Shea, David Rosenthal, Johanna Seibt, and Michael Williams – critically examines the groundbreaking ideas by means of which Sellars sought to integrate our thought, perception, and rational agency within a naturalistic outlook on reality. Topics include Sellars’s inferentialist semantics and normative functionalist view of the mind; his attempted reconciliations of internalist and externalist aspects of thought, meaning, and knowledge; his novel nominalist account of abstract entities; and a speculative ‘pure process’ metaphysics of consciousness. Of particular interest is how this volume exhibits the ongoing fruitful dialogue between so-called ‘left-wing Sellarsians’, who stress Sellars’s various Kantian and pragmatist defenses of the irreducibility of normativity and rationality within the space of reasons, and ‘right-wing Sellarsians’ who defend the plausibility of Sellars’s highly ambitious and systematic scientific naturalism. (shrink)

I sin udmærkede kommentar til vores artikel «En etisk diskussion af screening for kræftsygdomme» beskriver Geir Hoff den udtalte mangel på evidens vedrørende nytteværdien af screeningsprogrammer for kræftsygdomme baseret på randomiserede studier. Ydermere fremhæver Geir Hoff misforholdet mellem den manglende evidens ved screening og de strenge krav, der er til evidensen i den farmaceutiske industri. Dette er en velkommen kritik, pga. en udtalt ukritisk og uvidenskabelig tilgang til anvendelse af screening for denne eller hin sygdom eller risikofaktor.

Contending discourses underlie many of the worlds most intractable conflicts, producing misery and violence. This is especially true in the post-9/11 world. However, contending discourses can also open the way to greater dialogue in global civil society and across states and international organizations. This possibility holds even for the most murderous sorts of conflicts in deeply divided societies. In this timely and original book, John Dryzek examines major contemporary conflicts in terms of clashing discourses. Topics covered include the alleged (...) clash of civilizations; societies divided by ethnicity, nationality, or religion; economic globalization versus resistance; plus an in-depth discussion of the 'war on terror'. Dryzek concludes by highlighting the limitations of current neoconservative and cosmopolitan approaches, arguing that only deliberative global politics offers unprecedented new possibilities for democratic engagement in the international system. This book will be of interest to students and scholars of international relations, politics, philosophy, and sociology. (shrink)

The central dogma of biology holds that genetic information normally flows from DNA to RNA to protein. As a consequence it has been generally assumed that genes generally code for proteins, and that proteins fulfil not only most structural and catalytic but also most regulatory functions, in all cells, from microbes to mammals. However, the latter may not be the case in complex organisms. A number of startling observations about the extent of non-protein-coding RNA (ncRNA) transcription in the higher eukaryotes (...) and the range of genetic and epigenetic phenomena that are RNA-directed suggests that the traditional view of the structure of genetic regulatory systems in animals and plants may be incorrect. ncRNA dominates the genomic output of the higher organisms and has been shown to control chromosome architecture, mRNA turnover and the developmental timing of protein expression, and may also regulate transcription and alternative splicing. This paper re-examines the available evidence and suggests a new framework for considering and understanding the genomic programming of biological complexity, autopoletic development and phenotypic variation. BioEssays 25:930-939,2003. (C) 2003 Wiley Periodicals, Inc. (shrink)

The reviews of this book which greeted its appearance in America, where it won a Catholic Press Association Religious Book Award, speak for themselves. 'The real core of the book is the question that is raised - the demanding bone-crushing question we all face - alone - at one time - the question of death/life and immortality. In these few pages we set out on a journey - one that winds its way among ancient stories and myths ... one's constant (...) disturbing companion is death - a reality that keeps breaking in upon our imes, our friends, our dreams and hopes and even our changing and becoming. The richness of the book lies in the questioning and some of the answers other men's times have given in attempt to live with this probing. We meet Kazantzakis, Homer, Melville, Hegel, Dante in their humanness in the face of death and in their timeless answers' (National Catholic Reporter). From the Protestant side, Martin Marty commented how John Dunne, 'perhaps the most intuitive and natively talented Catholic around, has cast a new spell', and The Critic remarked: 'As a meditation ought to be, it is simple and profound at once. And it is beautifully done, in some ways the richest of John Dunne's works.' All of which amounts to an invitation to join the author as he poses the timeless dilemma of the human condition and seeks to resolve it through stories of adventures, journeys and voyages inspired by man's encounter with death; stories of childhood, youth, manhood and age; and finally stories of God and of man wrestling with God and the unknown. (shrink)

PART VII: PUBLICS AND MOVEMENTS. - PART VIII: GOVERNMENT RESPONSES. - PART IX: POLICY INSTRUMENTS. - PART X: PRODUCERS AND CONSUMERS. - PART XI: GLOBAL GOVERNANCE. - PART XII: RECONSTRUCTION.

Summarya) Bell tries to formulate more explicitly a notion of “local causality”: correlations between physical events in different space‐time regions should be explicable in terms of physical events in the overlap of the backward light cones. It is shown that ordinary relativistic quantum field theory is not locally causal in this sense, and cannot be embedded in a locally causal theory.b) Clauser, Home and Shimony criticize several steps in Bell's argument that any theory of local “beables” is incompatible with quantum (...) mechanics. It is contended that the Clauser‐Horne derivation of a Bell‐type inequality circumvents his weak steps. The Clauser‐Horne derivation must assume that there are no undetected correlations between choices of controllable variables in two space‐like separated regions. Methodological considerations support this assumption.c) In response to criticism by Shimony, Home, and Clauser, Bell tries to clarify the argument of “The theory of local beables”, and to defend as permissible the hypothesis of free variables.d) Bell's reply to an earlier criticism by Shimony, Clauser, and Home is answered. The convergence of Bell's position towards theirs is noted. (shrink)

Recent interpretations of Michel Foucault's work have leaned heavily on a reading that can be traced back to the 'vital ist/mechanist' debate in the philosophy of science from earlier in this century. Friends (Gilles Deleuze) and enemies (Jürgen Habermas) both read Foucault as a kind of vitalist, championing repressed and unrealized life-forces against a burdensome facticity. This reading of Foucault, however, comes with a prohibitively high cost: the giving up of Foucault's most trenchant insights regarding the nature of power. In (...) fact, Foucault has a quite different relation to the history and philosophy of science than the one ascribed to him by critics. Key Words: Bergson • Canguilhem • Foucault • opposition • vitalism. (shrink)

Geoffrey Rose’s prevention paradox points to a tension between two prima facie plausible moral principles: that we should save the greater number and that weshould save the most at risk. This paper argues that a novel moral theory, ex-ante contractualism, captures our intuitions in many prevention paradox cases, regardless of our interpretation of probability claims. However, it goes on to show that it might be impossible to square ex-ante contractualism with all of our moral intuitions. It concludes that even if (...) ex-ante contractualism cannot furnish an entire ethics of risk, it does identify important considerations for any such theory. (shrink)

A given but otherwise random environmental time series impinging on the input of a certain biological processor passes through with overwhelming probability practically undetected. A very small percentage of environmental stimuli, though, is ‘captured’ by the processor's nonlinear dissipative operator as initial conditions, and is ‘processed’ as solutions of its dynamics. The processor, then, is in such cases instrumental in compressing or abstracting those stimuli, thereby making the external world to collapse from a previous regime of a ‘pure state’ of (...) suspended animation into a set of stable complementary and mutually exclusive eigenfunctions or ‘categories'. The characteristics of this cognitive set depend on the operator involved and the hierarchical level where the abstraction takes place. Depending on the context, the transition from one state to another occurs in such a cognitive operator. The chaotic itinerancy may play a crucial role for this process. In this paper we model the dynamics which may underlie such a cognitive process and the role of the thalamo-cortical pacemaker of the brain. In order to model them, conceptualization by the notion of ‘attractor ruin’ in high-dimensional dynamical systems is necessary. (shrink)

The Buddha’s final illness, brought on by his last meal prior to his death, was traditionally seen as one of a set of ailments suffered by him at various points during his lifetime. This paper looks at different Buddhist explications of the causes of these ailments and applies them to the episode of the Buddha’s final illness. In both instances, three explanatory strategies are detected: the first stresses the causative importance of the Buddha’s own negative karmic deeds in past lives; (...) the second looks to the negative deeds and karma of others than the Buddha; the third offers non-karmic explanations. The first two engendered two rather different kinds of j?taka stories; the last did not involve any j?takas but highlighted various kinds of ‘natural’ explanations. (shrink)

One way of countering the objection that a global political order would lack the corresponding global political commitments is suggested by John Dryzek’s “Two paths to global democracy”. He argues that deliberative democracy simply does not require a shared identity or a strong adherence to a common public culture. All that is needed is a shared problem . According to Dryzek, the need to collectively solve problems is sufficient to generate a discursive engagement on the side of all those (...) concerned. In other words, the functional pressure of collective global problems might, by itself, create the necessary motivation to keep reciprocal modes of problem-solving going at the supranational level. (shrink)

Intelligent design theorist William Dembski hasproposed an ``explanatory filter'' fordistinguishing between events due to chance,lawful regularity or design. We show that ifDembski's filter were adopted as a scientificheuristic, some classical developments inscience would not be rational, and thatDembski's assertion that the filter reliablyidentifies rarefied design requires ignoringthe state of background knowledge. Ifbackground information changes even slightly,the filter's conclusion will vary wildly.Dembski fails to overcome Hume's objections toarguments from design.

The Congregation of the Doctrine of the Faith’s Dignitas personae does not offer a definitive rejection of the practice of human embryo adoption as intrinsically evil, but neither does it simply leave the matter an “open question.” The document does indeed oppose the practice, but its reasons for doing so are not clearly stated and seem to be in tension with its own affirmations of the personal dignity of embryos and the goodness of adoption. The Congregation’s opposition is therefore best (...) read as a prudential judgment that embryo adoption cannot be justified in the present circumstances due to the potential for scandal and the cooperation with the fertility industry which it involves. National Catholic Bioethics Quarterly 10.2 (Summer 2010): 307–328. (shrink)

Features Covers the philosophical and historical development of the concept of "species" Documents that variation was recognized by pre-Darwinian scholars Includes a section on the debates since the time of the New Synthesis Better suited to non-philosophers Summary Over time the complex idea of "species" has evolved, yet its meaning is far from resolved. This comprehensive work is a fresh look at an idea central to the field of biology by tracing its history from antiquity to today. Species is a (...) benchmark exploration and clarification of a concept fundamental to the past, present, and future of the natural sciences. In this edition, a section is added on the debate over species since the time of the New Synthesis, and brings the book up to date. A section on recent philosophical debates over species has also been added. This edition is better suited non-specialists in philosophy, so that it will be of greater use for scientists wishing to understand how the notion came to be that living organisms form species. (shrink)

Species concepts for bacteria and other microbes are contentious, because they are often asexual. There is a Problem of Homogeneity: every mutation in an asexual lineage forms a new strain, of which all descendents are clones until a new mutation occurs. We should expect that asexual organisms would form a smear or continuum. What causes the internal homogeneity of asexual lineages, if they are in fact homogeneous? Is there a natural “species concept” for “microbes”? Two main concepts devised for metazoans (...) and metaphytes have been applied to bacteria. One is the Recombination Concept, a revised form of the Biological Species Concept in which the homogenizing mechanism is the sharing of genome fragments, somewhat akin to sexual recombination. The other is the Ecological Species Concept, in which the ecological niche is that which maintains lineages as cohesive. In this paper I will discuss these two concepts, and offer an underlying model that conjoins them, and consider the implications for species concepts in general. In short, my argument is that asexual species are instances of the most primitive and underived notion of species, which I will call “quasispecies”, following Eigen, and that sexual species are merely one derived kind of species. Moreover, I will argue that there is a continuum of recombination from simple viral models in which each strain is a clone, through to obligate recombination of 50% of the parents’ genome, and that consequently there is no sharp division between “microbial” and more familiar species. (shrink)

Social and structural inequities shape health and illness; they are an everyday presence within the doctor-patient encounter yet, there is limited ethical guidance on what individual physicians should do. This paper draws on a study that explored how doctors and their professional associations ought to respond to the issue of social health inequities.

In lieu of an abstract, here is a brief excerpt of the content:Moral Distress: The Face of Workplace BullyingJohn S. MurrayAfter a 28–year long distinguished military career I accepted a research position in a tertiary academic health science center, which I considered to be my dream job following retirement. Initially I was to be responsible for one department. A second was added because of my expertise with disaster preparedness. Following my orientation, I immersed myself into my new roles recognizing that (...) there was much to be done to achieve the goal of getting both departmental research programs up to par with the rest of the organization. In a short time, I began to recognize one of my bosses was going to be challenging to work with.She expected that her name be included on all grant proposals and manuscripts despite making no substantial intellectual contributions to either. Additionally, she wanted unwarranted control over all research and scholarship activities I was engaged in with staff despite having no research experience. Even meeting with her to discuss my plans for the direction of research in this department, my efforts were met with argumentative and condescending behavior. She would agree to discuss my plans. When I showed up for meetings in her office she would get angry with me oftentimes for situations, which she herself created. I continued to move forward with my work feeling that how I had conducted research and scholarly work in the past, with integrity and uncompromising ethical standards, was going to be threatened. This created great moral stress for me. I felt overwhelmed, powerless and frustrated as a result of the uncertainty as to whether or not I could fulfill my responsibilities while still meeting moral obligations.Over time, my moral compass prevented me from deviating from the principles, which helped me to build a long–standing stellar reputation as a leader in the field of pediatric nursing. However, this came with a cost. Working for this particular boss was like being on an emotional rollercoaster. One day I would feel like she was pleased with my work, but the next day my efforts could be met with anger, demeaning and dismissive behaviors. Once she praised me in front of staff for the “great” work I was doing with the evidence–based practice initiative nurse leaders. The following day she reprimanded me for not working closely with this group. She was extremely well versed at singing my praises in front of staff. Behind her closed office door was a very different experience.I confided in some colleagues in this department how I was being treated. I quickly learned that all staff were treated in this manner by this one individual. They shared that condescending language and fear and intimidation were the norm. When [End Page 112] I asked them why no one had the awareness or courage to say this treatment was not right, they quickly shared with me that staff were deterred from speaking up for fear of greater bullying behaviors. Sadly, while everyone knew what was the right thing to do, institutional constraints made it nearly impossible to pursue the right course of action. It was readily apparent these nurses were missing advocacy. At that point, I decided it was important to seek a remedy to this problem recognizing it would be no easy task.Progressively, my work environment with this particular boss became intolerable. Despite working relentlessly to develop a research program, unwarranted criticism, unjustified blame, exclusion, isolation, unreasonable demands and denied opportunities persisted. By this time, I was suffering from nightmares, headaches, fear, anxiety, depression, difficulty concentrating, and problems with self–esteem. I felt like my professional competence and reputation was being unjustifiably denigrated by this one individual.In the past, I confided in trusted organizational leaders for guidance when faced with difficult situations. As such, I approached my other boss and shared what was happening. She was deeply concerned. She encouraged me to seek guidance from a safe and confidential environment where staff members can share concerns and receive assistance with how to handle these apprehensions. I had used a program like this in the past when dealing with moral distress. This experience was very helpful. In fact, I returned on multiple... (shrink)

Compiled in the second century B.C.E, the _Huainanzi_ clarifies a crucial period in the development of Chinese conceptions of the cosmos, human nature, and the social order. Outlining "all that a modern monarch needs to know," the text emphasizes rigorous self-cultivation and mental discipline, attributing successful rule to a balance of broad knowledge, diligent application, and penetrating wisdom. In 2010, the editors of this volume completed the first complete English-language translation of the _Huainanzi_, opening exciting new pathways in the study (...) of philosophy, Asian studies, political science, and Asian literature. This abridgement contains essential selections from each of the _Huainanzi_'s twenty-one chapters and adds a new introduction and chapter descriptions. The text represents a remarkable synthesis of Daoist classics, such as the _Laozi_ and the _Zhuangzi_; works associated with the Confucian tradition, such as the _Changes_, the _Odes_, and the _Documents_; and a range of other foundational philosophical and literary works, from the _Mozi_ to the _Hanfeizi_. The abridgement preserves the _Huainanzi_'s special rhetorical features, such as its parallel prose, verse, and unique compositional techniques. For decades, Western scholars overlooked the _Huainanzi'_s sophisticated structure, creative content, and rich historical value, yet all that changed with the translation of the full text. Designed for classroom use and general readers, _The Essential Huainanzi_ continues to increase awareness of this brilliant work and change our understanding of early Chinese history. (shrink)

Few have done more than Martin Gutzwiller to clarify the connection between classical time-dependent motion and the time-independent states of quantum systems. Hence it seems appropriate to include the following discussion of the origins of the time-dependent Schrödinger equation in this volume dedicated to him.

According to Plato, it is the aim of Philosophy to furnish us with a certain vision of all time and all existence. This must always have seemed a large and difficult undertaking; but the opening years of the present century have already introduced considerable changes in our estimation of magnitudes. We are learning to think of modes of existence that are much more minute and of others that are much larger than any that had previously been conceived with any definiteness. (...) Analysis now leads us to entities and processes that are almost inconceivably small; and synthesis points to a totality that is almost inconceivably great, and that may be even greater than we know. Our interests naturally begin with our human lives on earth ; and we are rapidly discovering that even these have to be thought of in ways that were hardly possible for any previous generation. In a sense, it may be said that our human world has been becoming much smaller. Distances within it are beginning to seem, in many respects, almost negligible ; and great hopes may be based upon this contraction. (shrink)

Over the past few years, blogging (“web logging”) has become a major social movement, and as such includes blogs by scientists about science. Blogs are highly idiosyncratic, personal and ephemeral means of public expression, and yet they contribute to the current practice and reputation of science as much as, if not more than, any popular scientific work or visual presentation. It is important, therefore, to understand this phenomenon.